EFFECTIVENESS OF ACTIVE CYCLE OF BREATHING TECHNIQUE (ACBT) WITH AND WITHOUT ACAPELLA IN IMPROVING AIRWAY CLEARANCE, DYSPNEA, AND PULMONARY FUNCTION IN COPD PATIENTS: A RANDOMIZED CONTROLLED TRIAL (2025)

Main Article Content

Mishal Sabir
Rizwanullah
Anna Bretches
Adela Damm
Shivani Shah
Rimsha Kausar

Keywords

COPD, Active Cycle of Breathing Technique, Acapella, airway clearance, dyspnea, pulmonary function tests, sputum diary, FEV1, FVC, randomized controlled trial

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) is a progressive inflammatory condition of the respiratory system, characterized by chronic bronchitis, airway thickening, and emphysema. Acapella, a handheld device with both resistive and vibratory properties, aids in airway clearance by loosening and mobilizing secretions. Research suggests that Active Cycle of Breathing Techniques (ACBTs) can be beneficial for COPD patients by improving lung function and facilitating secretion clearance. This study aims to evaluate the effects of ACBT with and without Acapella on airway clearance, dyspnea, and pulmonary function in COPD patients.


Objective: To assess the impact of ACBT alone versus ACBT combined with Acapella on airway clearance, dyspnea, and pulmonary function tests in COPD patients.


Methods: This randomized controlled trial was conducted at Aziz Bhatti Shaheed Teaching Hospital and National Hospital Gujrat. A total of 54 participants were randomly assigned to two groups after obtaining informed consent. Baseline assessments included a questionnaire evaluating dyspnea and sputum production, along with pulmonary function tests. One group performed ACBTs alone, while the other used ACBTs in combination with the Acapella device. The supervised intervention lasted for four weeks. Data was analyzed using SPSS 25.


Results: Within-group analysis revealed significant improvements in the control group for forced vital capacity (FVC) (p=0.034), forced expiratory volume in one second (FEV1) (p=0.014), dyspnea (p=0.001), other symptoms (p=0.005), and the affective dimension of the multi-dimensional profile (p=0.001). The treatment group, which used Acapella, demonstrated even greater improvements in FVC (p=0.001), FEV1 (p=0.005), dyspnea (p=0.011), well-being (p=0.001), and the affective dimension (p=0.014). Between-group comparisons showed significant differences in post-treatment values for FVC (p=0.023), FEV1 (p=0.004), dyspnea (p=0.003), and other symptoms (p=0.005).


Conclusion: The combination of Acapella with ACBTs is more effective than ACBTs alone in improving airway clearance, dyspnea, and pulmonary function in COPD patients.

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References

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Mishal Sabir, Rizwanullah, Anna Bretches, Adela Damm, Shivani Shah, & Rimsha Kausar. (2025). EFFECTIVENESS OF ACTIVE CYCLE OF BREATHING TECHNIQUE (ACBT) WITH AND WITHOUT ACAPELLA IN IMPROVING AIRWAY CLEARANCE, DYSPNEA, AND PULMONARY FUNCTION IN COPD PATIENTS: A RANDOMIZED CONTROLLED TRIAL. Journal of Population Therapeutics and Clinical Pharmacology, 32(1), 1018-1029. https://doi.org/10.53555/k6wt7w43

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EFFECTIVENESS OF ACTIVE CYCLE OF BREATHING TECHNIQUE (ACBT) WITH AND WITHOUT ACAPELLA IN IMPROVING AIRWAY CLEARANCE, DYSPNEA, AND PULMONARY FUNCTION IN COPD PATIENTS: A RANDOMIZED CONTROLLED TRIAL (1)

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Author Biographies

Mishal Sabir

Department of Rehabilitation and Allied Health Sciences, Riphah International University, Lahore, Pakistan

Rizwanullah

Department of Medicine, Hayatabad Medical Complex, Peshawar, Pakistan

Anna Bretches

Department of Physiotherapy, Bogomolets National Medical University, Kyiv, Ukraine

Adela Damm

Department of Medicine, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania

Shivani Shah

Department of Medicine, Carribean Medical University School of Medicine, Curacao, USA,

Rimsha Kausar

Department of Medicine, Ross University School of Medicine, Barbados, USA,

How to Cite

Mishal Sabir, Rizwanullah, Anna Bretches, Adela Damm, Shivani Shah, & Rimsha Kausar. (2025). EFFECTIVENESS OF ACTIVE CYCLE OF BREATHING TECHNIQUE (ACBT) WITH AND WITHOUT ACAPELLA IN IMPROVING AIRWAY CLEARANCE, DYSPNEA, AND PULMONARY FUNCTION IN COPD PATIENTS: A RANDOMIZED CONTROLLED TRIAL. Journal of Population Therapeutics and Clinical Pharmacology, 32(1), 1018-1029. https://doi.org/10.53555/k6wt7w43

  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
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  • IEEE
  • MLA
  • Turabian
  • Vancouver
  • AMA

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EFFECTIVENESS OF ACTIVE CYCLE OF BREATHING TECHNIQUE (ACBT) WITH AND WITHOUT ACAPELLA IN IMPROVING AIRWAY CLEARANCE, DYSPNEA, AND PULMONARY FUNCTION IN COPD PATIENTS: A RANDOMIZED CONTROLLED TRIAL (2025)
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